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Medications commonly used for symptomatic benefit of motor symptoms in early Parkinson disease include levodopa, monoamine oxidase (MAO)-B inhibitors, and dopamine agonists.
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Adverse effects (pramipexole): In placebo-controlled trials of early PD, the most commonly observed adverse events that were more numerous with pramipexole in more than 5% of patients were nausea, dizziness, somnolence, insomnia, constipation, asthenia, and hallucinations.
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Multifocal Dystonia: affects two or more distant regions of the body, such as the upper face and the hand.
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